Program Director:

Mukund SibiDr. Mukund Sibi, Professor / Chemistry -
Synthetic Organic Chemistry
Sibi Group Webpage

The Center is led by Dr. Mukund P. Sibi, James A. Meier and University Distinguished Professor, and 2008 winner of the Arthur C. Cope Scholar Award. Dr. Sibi was key to the program's inception in 2001.

 

Investigators:

Dr. Glenn Dorsam

Dr. Glenn Dorsam, Assistant Professor / Biochemistry
Dorsam Lab

Dr. Dorsam has established a research program based on the epigenetic transcriptional regulation controlling how cells proliferate and differentiate. He is specifically interested in the investigation of molecular mechanisms governing Ikaros-mediated transcriptional regulation of vasoactive intestinal peptide receptor-1 (VPACR-1) in T lymphocytes.

Dr. Gregory Cook, Associate Professor / Chemistry - Dr. Gregory Cook, Professor / Synthetic Organic Chemistry
Cook Group Webpage

Dr. Cook has initiated a vigorous program in the application of organometallic catalysis to organic synthesis with a focus on the preparation of unnatural amino acids. His group will use their amino acid expertise in the development of new protease inhibitors.


Dr. Bin GuoDr. Bin Guo, Associate Professor / Pharmaceutical Sciences
Guo Group Webpage

Dr. Guo has established a research program to study the regulation of cancer cell apoptosis. He is interested in the investigation of the molecular mechanisms that control cancer cell death in response to chemotherapeutic drugs.


Dr. Jane SchuhDr. Jane Schuh, Associate Professor / Immunology

Dr. Schuh's research program examines the development and maintenance of allergic asthma in an experimental murine model. She is particularly interested in the biology of chronic outcomes of the disease.


Doctor Sangita SinhaDr Sangita Sinha, Assistant Professor / Molecular Biophysics
sangita.sinha@ndsu.edu

Research interests are in structural biology with a focus on autophagy.


Dr Biga photoDr Peggy Biga, Assistant Professor / Biological Sciences
peggy.biga@ndsu.edu


Comparative Growth and Nutritional Physiology. Molecular and hormonal regulation of muscle growth and metabolism in vertebrates. Identification of the inter-regulation of muscle growth and regeneration and metabolic dysfunction utilizing murine and piscine model organisms. Characterization of model organism systems for muscle wasting disorder and regeneration.


Dr Greenlee photoDr Kendra Greenlee, Assistant Professor / Biological Sciences
kendra.green@ndsu.edu


Insect Physiology and Immunology. Research interests include body size variation and respiratory system physiology in insects, with an emphasis on the effects of hypoxia on respiratory functions and molting. I am also interested in insect immunity and the response to bacterial and parasite infections..


Dr John McEvoyDr John McEvoy, Associate Professor / Veterinary & Microbiological Sciences
john.mcevoy@ndsu.edu


Pathogenic Microbiology. Research Interests: Cryptosporidium virulence factors and mechanisms of pathogenesis. Academic Interests: Microbial pathogenesis.


Dr Chengwen SunDr Chengwen Sun, Assistant Professor / Pharmaceutical Sciences
chengwen.sun@ndsu.edu


Cardiovascular Pharmacology. My current research is focused on central blood pressure regulation and pathogenesis of hypertension to identify novel targets for the treatment of hypertension and other cardiovascular diseases.

 


photo of Katie ReindlDr Katie Reindl, Assistant Professor / Biological Sciences
katie.reindl@ndsu.edu


Dr Reindl's research program is aimed at validating new drug targets for cancer treatment. Currently, her lab group is investigating the expression, function, and regulation of peptide deformylase (PDF) and methionine aminopeptidase 1D (MAP1D), two potential molecular targets in various cancers.


photo of Steven QianDr Steven Qian, Assistant Professor / Pharmaceutical Sciences
steven.qian@ndsu.edu


Dr Qian is studying the roles of lipid metabolites from lipid peroxidation during progression/treatment of human diseases, including cancer. His group utilizes a novel technique, HPLC/ESR/MS, along with molecular biological techniques to assess the relationship between lipid-derived inflammatory molecules and COX/LOX expression during disease development/treatment.


photo of Pinjing ZhaoDr Pinjing Zhao, Assistant Professor / Organometallic Chemistry and Catalysis
pinjing.zhao@ndsu.edu


Research in the Zhao group focuses on mechanism-based rational design of new transition metal catalysis and applications towards synthesis of drugs and drug-like molecules.

 

 

Two Core Facilities play an integral part of the Center for Protease Research.They are designed to assist principle investigators with biomedical research and are excellent resources for assistance with data analysis, research consultations, and use of Core equipment.

Core Facility Managers:

doctor tao wangDr Tao Wang, Research Assistant Professor / Chemistry & Biochemistry
t.wang@ndsu.edu


Tao is the manager of our Core Biology Facility, which includes Tissue Culture, Molecular Biology, and Bioassay labs.
Visit the Core Biology Facility at: www.ndsu.edu/cpr/biology


Dr Ganesh Bala, Research Scientist / Chemistry & Biochemistry
n.balasubramanian@ndsu.edu

Ganesh manages the Core Synthesis & Analytical Services Facility, which specializes in the synthesis of small molecules for biomedical applications.
Visit the Core Synthesis Facility at: www.ndsu.edu/cpr/synthesis


 

 

Last updated: October 5, 2012