Likelihood Ratio Test For Discrete Classes

LOD Score

Example

Varying Q

Maximum Likelihood: Testcross Data

Plotting Lod Scores

Homework Assignment # 8 Questions

Homework Assignment #8 Answers

Homework Assignment # 8

Questions

  1. In the country of Utopia, there are exactly 260 cars. Each car has a license plate that is identified by one number and one letter. You have witnessed a car accident and report to the police that although you could not see the number on the license plate, the letter was 'R'.

    a) Find the conditional probability that the license
    a) plate is '2R' or Probability(2/R).

    b) Explain why the knowledge that the letter on
    b) the license plate is R increases the probability
    b) of identifying the car which was in the accident.

  2. Explain why selection for a homozygous RFLP marker genotype increases the probability of selecting a favorable QTL when the two loci are linked in coupling phase.

  3. A marker and a QTL are linked. Explain why as the percent recombination between a marker and a QTL increases, selection for the favorable QTL genotype will be less effective.

  4. You are selecting for a QTL based on data from a single marker locus. Explain why estimates of QTL means of each QTL genotype are confounded with the estimate of recombination between the marker and QTL.

Copyright 2000©, Ted Helms

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