F
Repulsion Progeny Part II
The A_B_ class has the proportion (p
+2)/4 for repulsion linkage. Now let us find the proportion
for the other three classes.
| class |
proportion |
A_bb
phenotype |
| AAbb |
(1-p)
4 |
| Aabb |
p(1-p)
4 |
| Aabb |
p(1-p)
4 |
(1-p)
+ p(1-p) + p(1-p)
= 1 - 2p + p
+ p - p
+ p - p
4 4 4 4
= -p
+ 1 = 1 - p
4 4
| class |
proportion |
| aaBB |
(1-p)
4 |
| aaBb |
p(1-p)
4 |
| aaBb |
p(1-p)
4 |
(1-p)
+ p(1-p) + p(1-p) = 1-p
4 4
Finally there is only one combination that results
in the aabb genotype with probability p
/4.
Example
We can sum the probability of all genotypes that are
phenotypically A_B_ or A_bb or aaB_, or aabb.
| class |
A_B_ |
A_bb |
aaB_ |
aabb |
Total |
| observed |
a |
a |
a |
a |
|
| observed |
753 |
292 |
351 |
19 |
1415 |
| expectation |
p2
+ 2
4 |
1-p2
4 |
1-p2
4 |
p2
4 |
|
r = n, s = -a
+ 2a
+ 2a
+ 2a
,
t = -2a
r = 1415, s = -753 + 2(292) + 2(351)
+ 2(19) = 571, t = -2(19) = -38
