Probability
Independent Events
Let A be one outcome of an event.
Let B be a second outcome of an event.
Probability (A) = probability that event A occurs.
Probability (B) = probability that event B occurs.
Probability (A and B) = probability that both events occur. If A and
B are independent events, then the probability of A occurring does not
influence the probability that event B occurs.
Probability(A and B) = P(A)P(B) = P(AB) when A and B are independent
events
Non-Independent Events
Now assume A and B are not independent events. If two
loci are linked and r < 0.5, then the probability
of a gamete containing an A allele is not independent
of the probability that the gamete contains the B allele.
An Independent Events Example
Locus one has two alleles, A and a.
Locus two has two alleles, B and b.
The two loci are on non-homologous chromosomes and are independent.
The testcross AaBb x aabb
1/4 AaBb
The testcross AaBb x aabb 1/4
aaBb
The testcross AaBb x aabb 1/4
Aabb
The testcross AaBb x aabb 1/4
aabb
Probability(A) = Probability(a) = Probability(B)
= Probability(b) = 1/2
Probability(AB) = 1/2(1/2) = 1/4
Probability(Ab) = 1/2(1/2) = 1/4
Probability(aB) = 1/2(1/2) = 1/4
Probability(ab) = 1/2(1/2) = 1/4
| |
(1-p)/2
AB |
p/2
aB |
p/2
Ab |
(1-p)/2
ab |
| 1ab |
AaBb
(1-p)/2 |
aaBb
p/2 |
Aabb
p/2 |
aabb
(1-p)/2 |