Probability Of An Allele In Testcross Progeny: Coupling
Phase
| |
AB |
ab |
Ab |
aB |
| ab |
AaBb
1-p
2 |
aabb
1-p
2 |
Aabb
p
2 |
aaBb
p
2 |

Repulsion Punnett Square
 |
p
2
AB |
1-p
2
Ab |
1-p
2
aB |
p
2
ab |
p
2
AB |
|
1-p
2
Ab |
1-p
2
aB |
p
2
ab |
Probability that two allemorphs are contained in the
same gamete is (In general):
P(AB) = (1-p)/2 for coupling
P(AB) = p/2 for repulsion
A and B loci are not independent unless p = 1/2
The following is true only when A
and B are independent:
If A and B loci are on two non-homologous chromosomes
or there is 50% recombination between loci on the same
chromosome, then:
P(A) P(B) = P(AB) due to A and B loci
segregating independently
P(A) = 1/2, P(B) = 1/2, then P(AB) = 1/4