Kristine Steffen, Pharm.D., Ph.D.
6B1 Sudro Hall
Office Phone: 701.231.5177
Lab Phone: 701.231.6303
1996-2000 B.S., Pharmaceutical Sciences,North Dakota State University, Fargo,ND
2000-2002 Pharm.D., Pharmacy Practice, North Dakota State University, Fargo,ND
2002-2007 Ph.D., Pharmaceutical Sciences, North Dakota State University, Fargo,ND
2007 College Teaching Certificate, North Dakota State University, Fargo,ND
Relevant Positions Held
Aug. 2012-Present: Associate Professor, Department of Pharmaceutical Sciences, College of Pharmacy, Nursing, and Allied Sciences, North Dakota State University, Fargo, ND
May 2009-Present: Research Scientist, Neuropsychiatric Research Institute, Fargo, ND
Dec 2007-May 2009: NRSA F32 Postdoctoral Fellowship sponsored by NIDDK, 1F32DK072895-01A1, Sponsoring Institution: Neuropsychiatric Research Institute, Fargo, ND.
Dec.2002-Dec.2007: Staff Pharmacist, MeritCare Hospital Pharmacy, Fargo, ND
Current Professional Societies and Public Advisory Committees
2004-Present: Academy of Eating Disorders (AED)
2004-Present: The Obesity Society (formerly North American Association for the Study of Obesity)
2009-Present: The American Society of Metabolic and Bariatric Surgery (ASMBS)
PSCI 470/670: Pharmacokinetics
Recent Selected Publications
Roerig, J.L., Steffen, K.J., Mitchell, J.E., Crosby, R.D., Gosnell B.A. (2008). A Comparison of the Effects of Olanzapine and Risperidone Versus Placebo on Ghrelin Plasma Levels. Journal of Clinical Psychopharmacology. Feb;28(1):21-6.
Roerig, J.L., Steffen, K.J., Mitchell, J.E., Crosby, R.D., Gosnell, B.A. (2009). An Exploration of the Effect of Modafinil on Olanzapine Associated Weight Gain in Normal Human Subjects. Biological Psychiatry, Apr 1;65(7):607-13
Steffen, K.J., Sarwer, D.B., Thompson, K.J., Mueller, A., Baker, A.W., Mitchell, J.E. (2012). Predictors of satisfaction with excess skin and desire for body contouring following bariatric surgery. Surgery for Obesity and Related Diseases, 8(1):92-7.
Mitchell, J.E., Steffen, K.J., Crosby, R., Engel, S. & Roerig, J. (2010). Psychopharmacologic trials in eating disorders. In M. Hertzman & L. Adler (Eds.), Clinical Trials in Psychopharmacology: A Better Brain. London : John Wiley & Sons, Ltd.
Roerig J, Steffen K, Mitchell JE, Zunker, C. (2010). Laxative abuse: epidemiology, diagnosis and management. Drugs, Aug 20;70(12).
Gosman C.G., King W.C., Schrope B., Steffen K.J., Strain G.W., Courcoulas A.P., Flum D.R., Pender J.R. (2010). Reproductive Health of Women Electing Bariatric Surgery. Fertil Steril. Sep;94(4):1426-31. (Additional Author Reply May 28, 2010). PMCID: PMC2888936.
Steffen, K.J., Mitchell, J.E. Overview of Treatment for Compulsive Buying. (2010). In Compulsive Buying: Clinical Foundations and Treatment. Edited by A. Muller and J. Mitchell. Routledge.
Sarwer, D.B., Faulconbridge, L.F., Mitchell, J.E., Steffen, K.J., Roerig, J.L. (2011). The
Management of Mood Disorders with Anti-depressant Medications After Bariatric Surgery. Current Psychiatry.
Steffen, K.J., Roerig, J.L, Engel, J.E. (2011). Psychopharmacology Pre and Post Bariatric Surgery. Chapter in Psychological Assessment and Treatment of Bariatric Surgery Patients. Edited by J. Mitchell and M. deZwaan.
King W.C., Chen J.Y, Mitchell, J.E., Kalarchian, M.A., Steffen, K.J., Engel, S.G., Courcoulas, A.P., Pories W.J., Yanovski, S.Z. (2012). Prevalence of alcohol use disorders before and after bariatric surgery. JAMA. 20;307(23):2516-25.
Roerig, J.L., Steffen, K.J., Mitchell, J.E., Crosby, R.D. (2012). A preliminary comparison of sertraline blood levels in post-bariatric surgery patients versus matched nonsurgical control subjects. Surgery for Obesity and Related Diseases, 8(1):62-6.
Grant Support as PI
04/01/10 - 03/31/15 1K23DK085066-01, Pharmacokinetics Post-bariatric Surgery
- This is a K23 award to study pharmacokinetic changes on sertraline longitudinally prior to and following gastric bypass surgery. Mentors: James E. Mitchell, M.D., James L. Roerig, Pharm.D., Cheryl L. Zimmerman, Ph.D., Ross D. Crosby, Ph.D.
09/01/09 – 08/31/121R03AA019573-01,Steffen and Engel (Co-PI’s),Alcohol Use Before and After Bariatric Surgery
- This is a study designed to investigate the use of alcohol in pre and post bariatric surgery patients using ecological momentary assessment, as well as investigate the pharmacokinetic aspects of alcohol in post-surgery patients in the laboratory.
2006-2009, 1F32DK072895-01A1, A Randomized, Double-Blind, Placebo-Controlled Trial Evaluating the Effects of Bupropion SR on Food Craving and Weight in Overweight and Obese Human Subjects.