NDSU Guides

Center for Nutrition and Pregnancy


Research

Currently, studies in a variety of species (primarily sheep, swine, and cattle) are designed to understand how the following factors/stressors impact fertility as well as fetal and postnatal growth and development, and therefore health and productivity, of the offspring:

  • Maternal nutritional intake around the time of conception
  • Maternal nutritional intake during pregnancy
  • Specific nutrients, such as selenium and protein, in the maternal diet
  • Maternal nutritional intake during early lactation
  • Maternal activity/exercise
  • Maternal exposure to steroid hormones (e.g., corticoids, estrogens)
  • Maternal age (e.g., adolescence)
  • Maternal or fetal genotype
  • Singleton vs. multiple fetuses/offspring
  • Sex of the fetus/offspring
  • Assisted reproductive techniques including in vitro fertilization and cloning

 

Research Projects (PIs and Co-PIs listed)

  1. Reynolds LP and Grazul-Bilska AT, PHS Grant R03HD076073, “Steroid receptors in placental tissue and vasculature during early pregnancy;” $100,000 total direct costs, April 2014-March 2016
  2. Reynolds LP and Conley AJ, Academic Scholarship Fund, Society for Reproduction and Fertility, “Steroids in regulation of parturition, fetal maturation, and placental expulsion in cows;” £10,000 (approx. $16,000); November 2014-January 2016
  3. Reynolds LP and Conley AJ, USDA-AFRI Grant, “Role of placental, fetal adrenal and fetal neural steroids in parturition and extra-uterine survival;” $131,396 total direct costs, September 2013-August 2015
  4. Reynolds LP, Caton JS, USDA Hatch Project, “Regulation of Fertility in Ruminant Livestock;” salary support for PIs and operating funds, December 2013-September 2018
  5. Reynolds LP, Redmer DA, Wallace JM, PHS Grant R01HD045784-05S2, “Administrative Supplement” (Parent Grant, NICHD 45784-01-05 “Nutrition, fetal growth, and placental angiogenesis”); $197,514 total direct costs, August 2010-July 2012
  6. O’Rourke ST, PHS Grant NHLBI R03-HD061532-01-02, “Undernutrition in Pregnancy and Developmental Programming of Vascular Function”; $100,000 total direct costs, September 2009-August 2013
  7. Reynolds LP, Redmer DA, Wallace JM, PHS Grant R01HD045784-05S1, “Summer Research Experience” (Parent Grant, NICHD 45784-01-05 “Nutrition, fetal growth, and placental angiogenesis”; $4,302 total direct costs, June 2009-October 2009
  8. Reynolds LP and Grazul-Bilska AT, USDA, NRI Grant 2007-01215, “Epigenetics of placental angiogenesis in cloned and monoparental sheep fetuses”; $315,000 total direct costs, September 2007-August 2011
  9. Reynolds LP, Myatt L, Hay W, USDA, NRI Conference Grant – Aspen Perinatal Biology Symposium, “Interaction of Maternal, Placental and Fetal Systems in Perinatal Development”; $10,000 total direct costs, July 2007-August 2008
  10. Reynolds LP, Redmer DA, USDA Hatch Project, “Angiogenesis and Reproduction in Livestock;” salary support for PIs and operating funds, January 2007-September 2012
  11. Reynolds LP, Redmer DA, Wallace JM, PHS Grant NICHD 45784-01-05 “Nutrition, fetal growth, and placental angiogenesis”; $1,210,000 total direct costs; April 2005-March 2011
  12. Reynolds LP, Magness RR, Hay W, USDA, NRI Conference Grant – FASEB Summer Research Conference “Molecular & Cellular Signaling in the Perinatal Cardiovascular System”; $10,000 total direct costs, August 2004-July 2005
  13. Reynolds LP and Redmer DA, PHS Grant NHLBI 64141-01-04 “The major angiogenic factors in placental angiogenesis”; $425,000 total direct costs; February 2001-January 2005