Department of Chemistry and Biochemistry (Conference/Workshop/Seminar)
Stefan Vetter, Research Assistant Professor, Department of Pharmaceutical Sciences, North Dakota State University, Fargo, will present a seminar entitled, "A Multidisciplinary Approach to Understanding the Molecular Mechanisms of the Receptor for Advanced Glycation Endproducts".
Everyone is welcome!
The Receptor for Advanced Glycation Endproducts (RAGE) is a multi-ligand, cell surface receptor and recognizes several extracellular ligands that are associated with tissue injury. Overactivation of RAGE contributes to the development and progression of a surprisingly broad spectrum of diseases, including vascular disease, diabetic complications, neurodegeneration, and certain cancers.
The presentation will focus on our multidisciplinary approach to understanding two specific aspects of RAGE.:
1) How does the receptor interact with structurally dissimilar ligands?
2) How can we develope small molecules that block RAGE activation and could become therapeutically useful? More information...
Department of Chemistry and Biochemistry
Wendy J. Leach firstname.lastname@example.org
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