NDSU Calendar

Thursday, March 7, 2013
11:00am
Department of Chemistry and Biochemistry (Conference/Workshop/Seminar)

Mi Hye Song, Department of Biological Sciences, Michigan Technological University, Houghton, MI will present a seminar entitled, "Mechanisms of Centrosome Assembly and its Link to the Cell Cycle".
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Everyone is Welcome!
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Abstract:
Centrosomes are the primary microtubule organizing centers in animal cells, and have a critical role in establishing bipolar spindles. To maintain the fidelity of cell division, the number and structure of centrosomes must be precisely regulated, duplicating exactly once per cell cycle. Errors in centrosome duplication result in too few or too many centrosomes, leading to mis-segregation of chromosomes. Genomic instability, a feature of many cancers, is often associated with aberrant centrosomes and multiple centrosomes suffice to promote genomic instability and tumors. Thus, understanding the molecular and genetic mechanisms of centrosomes assembly should enhance our knowledge of cancer and other human diseases in which this process goes awry. My research is to contribute to further comprehension of centrosome assembly and its link to the cell cycle, by using a combination of "biochemistry, molecular cell biology, genetics, omics, quantitative confocal imaging, and NextGen sequencing in the nematode Caenorhabditis elegans model."
More information...
Location: Ladd 107
Price: Free
Host: Department of Chemistry and Biochemistry
Contact: Wendy J. Leach
E-Mail: wendy.leach@ndsu.edu

701-231-8694

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