Dr. Dorsam has been studying VIP for two decades. Recently, he began asking whether VIP is important in shaping the community of microbes that inhabit the gut. Dr. Matt Bains, who graduated from the our PhD program in 2018, was first author on this paper in Frontiers in Microbiology that used 16S rRNA sequencing to examine the bacterial community in the gut of mice with normal VIP expression and with VIP genetically removed. The research has shown that removal of VIP leads to altered microbial communities and weight loss in the gut of male and female mice. Read more here.
New paper from Dorsam Lab
Vasoactive Intestinal Peptide (VIP) has critical roles in gut health. This new research shows that those roles include maintaining microbiota balance and biodiversity.