Department of Physics


Department of Physics Apple - Gravity

Phone (701) 231-8974, fax (701) 231-7088


Seminar Abstract

October 2, 2002:

"Computer Simulations for Predicting Protein-Protein
and Protein-DNA Interactions
"

Professor Kathryn Thomasson
Department of Chemistry
University of North Dakota

The method of Brownian dynamics will be described as a useful tool for studying the interactions between large macromolecules of biological importance. Applications include: (1) Interactions of the genome regulatory protein 434 Cro repressor with DNA and (2) Interactions of the glycolytic enzymes aldolase, GAPDH, and triose phosphate isomerase with the cytoskeletal structure F-actin.