RFLP and Genetic Screening

PCR Analysis of the Cystic Fibrosis Gene

Linked DNA Markers

Study Questions

Molecular Markers WWW Links

Genetic Topics

Study Questions

  1. Describe the steps necessary for a restriction fragment length polymorphism (RFLP) study.
  2. Explain the statement that each RFLP is unique to a specific enzyme/probe combination
  3. How was PCR technology applied to the clinical analysis of cystic fibrosis?
  4. What is the relationship between Mendel's second law of genetics (law of independent assortment) and linked DNA marker analysis?
  5. If you read the statement that "a marker will diagnose a gene with 99% accuracy", what does that mean to you in terms of genetic linkage?
Copyright © 1997. Phillip McClean