Proof that DNA is Genetic Material
GriffithWhen he added dead, virulent pneumonia bacteria to a mouse, it lived; but if he added dead virulent bacteria to live non-virulent bacteria some mice died. He termed the material that changed the non-virulent bacteria to virulent the transforming principle.
Avery, MacLeod and McCartyThey used biochemical purification of cellular fractions to determine that DNA and not RNA or protein was the transforming principle.
Transformation - the alteration of phenotype by the addition of foreign DNA
Hershey and Chase The "Blender Experiment"They knew that:
Protein - has S but not P
Copyright © 1998. Phillip McClean