Bovine Abortion Diagnostic Panel Work-Up

Common differential list:

  • Bacteria: Ureaplasma diversum, Salmonella spp., Campylobacter spp., Brucella spp., Trueperella pyogenes, opportunistic bacteria (Bacillus spp. etc.), Leptospira spp., Listeria monocytogenes
  • Viruses: BoHV-1 (IBR), BVDV
  • Protozoa: Neospora caninum, Sarcocystis spp
  • Fungal: Aspergillus spp., Mucor spp., Candida spp.
  • Nutritional
  • Toxicities: Nitrate, ergot

Samples to submit (fresh and fixed):

  • Heart
  • Lymph node
  • Liver
  • Brain: whole brain fresh
  • Lung
  • Skeletal muscle/tongue/diaphragm
  • Kidney
  • Eyelid/conjunctiva
  • Spleen
  • Fetal eye/vitreous humor
  • Abomasal fluid
  • Thymus
  • Thyroid
  • Thoracic fluid
  • Adrenal glands
  • Small and large intestines
  • Placenta: 2-3 cotyledons with intercotyledonary placenta and amnion
  • Any additional gross lesions

Standard tests run at the laboratory (included in the general investigation):

  • Histopathology
  • Abortion and Campylobacter spp. cultures
  • Bovine abortion multiplex PCR (BoHV-1, BVDV)

Additional tests (check website for preferred samples and current prices):

  • Trace mineral analysis
  • Nitrates
  • PCR for Neospora caninum or Ureaplasma diversum
  • Vitamin A and E*
  • Serology (maternal or fetal)
    • Abortion Panel-bovine serology comprehensive *
  • Leptospira Panel (5 serovars), Neopsora caninum, Brucella abortus, BoHV-1, and BVDV types 1A, 1B, and 2
    • IgG * (fetal heart blood or thoracic fluid)

      *Indicates referral test

Printable version here.

Updated June 26, 2026