Bovine Neurologic Diagnostic Panel Work-Up
History (neuroanatomical localization and clinical signs are crucial for these cases and will guide diagnostic testing).
Common differential list:
- Bacteria: Histophilus somni, Listeria monocytogenes
- Viruses: Rabies, MCF, WNV, BoHV-1
- Protozoal: Neospora caninum, Sarcocystis spp.
- Toxicities: Sulfur toxicity, water deprivation/salt toxicity, lead toxicity
- Nutritional: Thiamine deficiency, plants
- Parasites: Eimeria spp. (no lesions in brain)
Samples to submit (fresh and fixed):
- Brain: whole brain fresh
- Liver
- Heart
- Kidney
- Skeletal muscle
- Omasum
- Colon
- Feces
- Eye
- Spinal cord
- Serum
- Ruminal contents, complete feed, water
- Any other gross lesions
Standard tests run at the laboratory (included in the general investigation):
- Histopathology
- Aerobic culture
- Direct fluorescent antibody assay (rabies)
Additional tests (check website for preferred samples and current prices):
- Trace mineral analysis
- Case-by-case basis: depending on clinical history and lesions
- PCR for viral and protozoal organisms
Updated 01/10/2025