Erxi Wu, assistant professor of pharmaceutical sciences, presented a poster titled “PDGFR alpha and PDGFR beta Differentially Regulate Cell Proliferation and Migration/Invasion in Medulloblastoma Cells” at the 2009 International Association for Biological and Medical Research annual meeting in Boston on Nov 19. Fengfei Wang, senior research associate in Wu's laboratory, is first author for the poster.
“Our presented data suggest that platelet derived growth factor receptor (PDGFR) alpha and PDGFR beta play different roles in cell proliferation and migration/invasion in medulloblastoma brain tumor cells. These studies also highlight the potential of targeting PDGFRs signaling therapy in medulloblastoma,” Wu said, “We are excited about these findings, and we are in the process of writing a manuscript.”
The International Association for Biological and Medical Research is a not-for-profit organization founded in 2002. The association is registered and headquartered in Boston. Its major mission is to provide a platform of professional interaction and collaboration among the international biomedical research community. Wu served as president from 2002-03.
Wu's laboratory research interests include tumor therapeutic targets, drug discovery and biomarkers. Both Wu and Wang joined NDSU in December 2008. Prior to joining NDSU, both Wu and Wang worked at Harvard University.